{"id":2888,"date":"2023-12-01T17:36:26","date_gmt":"2023-12-01T16:36:26","guid":{"rendered":"https:\/\/lipogems.oniroagency.com\/lipogems-system\/tessuto-adiposo-risposta-danno\/"},"modified":"2024-05-06T14:14:26","modified_gmt":"2024-05-06T13:14:26","slug":"the-adipose-tissue-damage-response-mechanism","status":"publish","type":"page","link":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/","title":{"rendered":"The adipose tissue damage response mechanism"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row css=&#8221;.vc_custom_1701446209808{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text css=&#8221;&#8221; text_align=&#8221;center&#8221;]Today it is widely recognized that in response to local tissue injury or inflammation, the body responds in a complex set of ways aimed at controlling the micro-environment. Because adipose tissue provides not only cushioning and support of so many normal tissues in the body, but also plays a role in the biochemical homeostasis of these tissues, it is only natural to expect the involvement of adipose tissue in the normal healing response setting. To this end, retention of the cellular and tissue microarchitecture of adipose tissue is important in maximizing the impact during normal healing processes.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=&#8221;Scientific publications&#8221; font_container=&#8221;tag:h2|text_align:center&#8221; use_theme_fonts=&#8221;yes&#8221; css=&#8221;&#8221;][vc_column_text css=&#8221;&#8221; width=&#8221;700&#8243; text_align=&#8221;center&#8221;]Please see below some relevant papers on the damage response mechanism.[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_class=&#8221;riga-box-pdf&#8221;][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Caplan-2006.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">Mesenchymal Stem Cells as Trophic Mediators<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Caplan-2008.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">All MSCs Are Pericytes?<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Caplan-2011.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">The MSC: An Injury Drugstore<\/h3><\/div><\/a>[\/vc_column][\/vc_row][vc_row el_class=&#8221;riga-box-pdf&#8221;][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Crisan-2008.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Feng-2011.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">Dual origin of mesenchymal stem cells contributing to organ growth and repair<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Mills-2013.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">Pericytes, Mesenchymal Stem Cells and the Wound Healing Process<\/h3><\/div><\/a>[\/vc_column][\/vc_row][vc_row el_class=&#8221;riga-box-pdf&#8221;][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Somoza-2016.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">Roles for mesenchymal stem cells as medicinal signaling cells<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;]<a class=\"vcex-module vcex-icon-box vcex-icon-box-one vcex-icon-box-has-link wpex-inherit-color wpex-no-underline wpex-flex wpex-items-center wpex-text-left\" href=\"\/wp-content\/uploads\/2023\/12\/Krasnodembskaya-2010.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><div class=\"vcex-icon-box-symbol wpex-flex-shrink-0 wpex-mr-20\"><div class=\"vcex-icon-box-icon wpex-inline-flex wpex-items-center wpex-justify-center wpex-child-inherit-color wpex-text-center wpex-leading-none wpex-text-1\"><span class=\"ticon ticon-file-pdf-o\" aria-hidden=\"true\"><\/span><\/div><\/div><div class=\"vcex-icon-box-text wpex-flex-grow\"><h3 class=\"vcex-icon-box-heading wpex-heading wpex-text-md wpex-mb-10\">Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37<\/h3><\/div><\/a>[\/vc_column][vc_column width=&#8221;1\/3&#8243;][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row css=&#8221;.vc_custom_1701446209808{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text css=&#8221;&#8221; text_align=&#8221;center&#8221;]Today it is widely recognized that in response to local tissue injury or inflammation, the body responds in a complex set of ways aimed at controlling the micro-environment. Because adipose tissue provides not only cushioning and support of so many normal tissues in the body, but also plays a role&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":2873,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-2888","page","type-page","status-publish","hentry","entry","no-media"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The adipose tissue damage response mechanism | Lipogems<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The adipose tissue damage response mechanism | Lipogems\" \/>\n<meta property=\"og:description\" content=\"[vc_row css=&#8221;.vc_custom_1701446209808{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text css=&#8221;&#8221; text_align=&#8221;center&#8221;]Today it is widely recognized that in response to local tissue injury or inflammation, the body responds in a complex set of ways aimed at controlling the micro-environment. Because adipose tissue provides not only cushioning and support of so many normal tissues in the body, but also plays a role&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/\" \/>\n<meta property=\"og:site_name\" content=\"Lipogems\" \/>\n<meta property=\"article:modified_time\" content=\"2024-05-06T13:14:26+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/\",\"url\":\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/\",\"name\":\"The adipose tissue damage response mechanism | Lipogems\",\"isPartOf\":{\"@id\":\"https:\/\/www.lipogems.com\/en\/#website\"},\"datePublished\":\"2023-12-01T16:36:26+00:00\",\"dateModified\":\"2024-05-06T13:14:26+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.lipogems.com\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lipogems\u00ae system\",\"item\":\"https:\/\/www.lipogems.com\/en\/lipogems-system\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"The adipose tissue damage response mechanism\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.lipogems.com\/en\/#website\",\"url\":\"https:\/\/www.lipogems.com\/en\/\",\"name\":\"Lipogems\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.lipogems.com\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.lipogems.com\/en\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.lipogems.com\/en\/#organization\",\"name\":\"Lipogems\",\"url\":\"https:\/\/www.lipogems.com\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.lipogems.com\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.lipogems.com\/wp-content\/uploads\/2023\/07\/Lipogems_Logo_white.svg\",\"contentUrl\":\"https:\/\/www.lipogems.com\/wp-content\/uploads\/2023\/07\/Lipogems_Logo_white.svg\",\"caption\":\"Lipogems\"},\"image\":{\"@id\":\"https:\/\/www.lipogems.com\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The adipose tissue damage response mechanism | Lipogems","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/","og_locale":"en_US","og_type":"article","og_title":"The adipose tissue damage response mechanism | Lipogems","og_description":"[vc_row css=&#8221;.vc_custom_1701446209808{margin-bottom: 40px !important;}&#8221;][vc_column][vc_column_text css=&#8221;&#8221; text_align=&#8221;center&#8221;]Today it is widely recognized that in response to local tissue injury or inflammation, the body responds in a complex set of ways aimed at controlling the micro-environment. Because adipose tissue provides not only cushioning and support of so many normal tissues in the body, but also plays a role&hellip;","og_url":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/","og_site_name":"Lipogems","article_modified_time":"2024-05-06T13:14:26+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/","url":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/","name":"The adipose tissue damage response mechanism | Lipogems","isPartOf":{"@id":"https:\/\/www.lipogems.com\/en\/#website"},"datePublished":"2023-12-01T16:36:26+00:00","dateModified":"2024-05-06T13:14:26+00:00","breadcrumb":{"@id":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.lipogems.com\/en\/lipogems-system\/the-adipose-tissue-damage-response-mechanism\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.lipogems.com\/en\/"},{"@type":"ListItem","position":2,"name":"Lipogems\u00ae system","item":"https:\/\/www.lipogems.com\/en\/lipogems-system\/"},{"@type":"ListItem","position":3,"name":"The adipose tissue damage response mechanism"}]},{"@type":"WebSite","@id":"https:\/\/www.lipogems.com\/en\/#website","url":"https:\/\/www.lipogems.com\/en\/","name":"Lipogems","description":"","publisher":{"@id":"https:\/\/www.lipogems.com\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.lipogems.com\/en\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.lipogems.com\/en\/#organization","name":"Lipogems","url":"https:\/\/www.lipogems.com\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.lipogems.com\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.lipogems.com\/wp-content\/uploads\/2023\/07\/Lipogems_Logo_white.svg","contentUrl":"https:\/\/www.lipogems.com\/wp-content\/uploads\/2023\/07\/Lipogems_Logo_white.svg","caption":"Lipogems"},"image":{"@id":"https:\/\/www.lipogems.com\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/pages\/2888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/comments?post=2888"}],"version-history":[{"count":2,"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/pages\/2888\/revisions"}],"predecessor-version":[{"id":2890,"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/pages\/2888\/revisions\/2890"}],"up":[{"embeddable":true,"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/pages\/2873"}],"wp:attachment":[{"href":"https:\/\/www.lipogems.com\/en\/wp-json\/wp\/v2\/media?parent=2888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}